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SOX10 monoclonal antibody, clone SOX10/1074

  • Catalog # : MAB14443
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human SOX10.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 115-269 of human SOX10.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 49-58
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • Recognizes a protein of ~55kDa, identified as SOX10. This antibody is highly specific and does not cross-react with other members of the SOX-family.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/million cells)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA and 0.05% azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: recombinant protein, Lane 2: A375 cell lysates with SOX10 monoclonal antibody, clone SOX10/1074 (Cat # MAB14443).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of (A) human melanoma and (B) mouse brain with SOX10 monoclonal antibody, clone SOX10/1074 (Cat # MAB14443).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 6663
  • Gene Name:
  • SOX10
  • Gene Alias:
  • DOM,MGC15649,WS2E,WS4
  • Gene Description:
  • SRY (sex determining region Y)-box 10
  • Gene Summary:
  • This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028515,OTTHUMP00000195094,SRY-related HMG-box gene 10,dominant megacolon, mouse, human homolog of
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