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HCG Holo monoclonal antibody, clone HCGab/52

  • Catalog # : MAB14427
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against intact-HCG.
  • Immunogen:
  • Native purified hCG protein.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Reacts only with the intact-HCG and not with either free alpha- or free beta-chain of HCG.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA and 0.05% azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with HCG Holo monoclonal antibody, clone HCGab/52 (Cat # MAB14427).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 1081
  • Gene Name:
  • CGA
  • Gene Alias:
  • CG-ALPHA,FSHA,GPHA1,GPHa,HCG,LHA,TSHA
  • Gene Description:
  • glycoprotein hormones, alpha polypeptide
  • Gene Summary:
  • The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016825,chorionic gonadotropin, alpha polypeptide,follicle-stimulating hormone alpha subunit
  • Gene Information
  • Entrez GeneID:
  • 1082
  • Gene Name:
  • CGB
  • Gene Alias:
  • CGB3,hCGB
  • Gene Description:
  • chorionic gonadotropin, beta polypeptide
  • Gene Summary:
  • This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq
  • Other Designations:
  • chorionic gonadotropin beta 3 subunit,chorionic gonadotropin beta chain,chorionic gonadotropin beta subunit
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