PAX7 monoclonal antibody, clone PAX7/1187
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PAX7.
Immunogen
Recombinant protein corresponding to amino acids 301-505 of human PAX7. (exact sequence is proprietary)
Host
Mouse
Theoretical MW (kDa)
57
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL for 30 min at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rhabdomyosarcoma (A) and human testicular carcinoma (B) with PAX7 monoclonal antibody, clone PAX7/1187 (Cat # MAB14392). -
Gene Info — PAX7
Entrez GeneID
5081Protein Accession#
P23759Gene Name
PAX7
Gene Alias
HUP1, PAX7B
Gene Description
paired box 7
Gene Ontology
HyperlinkGene Summary
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000002534|PAX7 transcriptional factor|paired box gene 7|paired box homeotic gene 7|paired domain gene 7
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Interactome
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Disease
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