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MUC3 monoclonal antibody, clone MUC3/1154

  • Catalog # : MAB14366
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of human MUC3.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to a 35 amino acid fragment, SIB35, which contains two tandem repeats of human MUC3.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 1100
  • Reactivity:
  • Human
  • Specificity:
  • This monoclonal antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gastric carcinoma (A, B) and human colon carcinoma (C) with MUC3 monoclonal antibody, clone MUC3/1154 (Cat # MAB14366).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4584
  • Protein Accession#:
  • Q02505;Q9H195
  • Gene Name:
  • MUC3A
  • Gene Alias:
  • MUC3,mucin
  • Gene Description:
  • mucin 3A, cell surface associated
  • Gene Summary:
  • The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM
  • Other Designations:
  • mucin 3, intestinal,mucin 3A, intestinal
  • Gene Information
  • Protein Accession#:
  • Q02505;Q9H195
  • Gene Name:
  • MUC3B
  • Gene Alias:
  • MUC3,MUC3A
  • Gene Description:
  • mucin 3B, cell surface associated
  • Other Designations:
  • intestinal mucin MUC3B,mucin 3B
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