TOP1MT monoclonal antibody, clone TOP1MT/488
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gallbladder (A), human melanoma (B) and human pancreas (C) with TOP1MT monoclonal antibody, clone TOP1MT/488 (Cat # MAB14240).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human TOP1MT.
Immunogen
Recombinant protein corresponding to full length human TOP1MT.
Host
Mouse
Theoretical MW (kDa)
70
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gallbladder (A), human melanoma (B) and human pancreas (C) with TOP1MT monoclonal antibody, clone TOP1MT/488 (Cat # MAB14240).Immunofluorescence
Flow Cytometry
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Gene Info — TOP1MT
Entrez GeneID
116447Protein Accession#
Q969P6Gene Name
TOP1MT
Gene Alias
2900052H09Rik
Gene Description
topoisomerase (DNA) I, mitochondrial
Omim ID
606387Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of DNA which allows the strands to pass through one another and relieves the stress introduced by a circular mitochondrial genome during replication and transcription. [provided by RefSeq
Other Designations
mitochondrial topoisomerase I
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Interactome
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Disease
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