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ESR2 monoclonal antibody, clone ERb455 (PE)

  • Catalog # : MAB14209
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human ESR2.
  • Immunogen:
  • Recombinant protein corresponding to the C-terminus of human ESR2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 53-59
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry (5 uL/test/million cells in 0.1 mL or 5 uL/100 uL of whole blood)
    Immunofluorescence (1:50-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of MCF-7 cell with ESR2 monoclonal antibody, clone ERb455 (PE) (Cat # MAB14209) (red). Black: cells alone. Green: isotype control.
  • Application Image
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 2100
  • Gene Name:
  • ESR2
  • Gene Alias:
  • Gene Description:
  • estrogen receptor 2 (ER beta)
  • Gene Summary:
  • This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq
  • Other Designations:
  • estrogen receptor beta,estrogen receptor beta 4
  • Related Disease
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