CD99 monoclonal antibody, clone 12E7

Catalog # MAB14199

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Quantity

Size:500 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human Ewing's sarcoma with CD99 monoclonal antibody, clone 12E7 (Cat # MAB14199).

  • Specification

    Product Description

    Mouse monoclonal antibody raised against native human CD99.

    Immunogen

    Human acute lymphocytic leukemia T-cells.

    Host

    Mouse

    Theoretical MW (kDa)

    27-32

    Reactivity

    Human

    Form

    Liquid

    Isotype

    IgG1, kappa

    Recommend Usage

    Flow Cytometry (5-10 uL/million cells in 0.1 mL)
    Immunofluorescence (1:50-1:100)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:100)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In tissue culture supernatant (0.05% sodium azide).

    Storage Instruction

    Store at 4°C.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human Ewing's sarcoma with CD99 monoclonal antibody, clone 12E7 (Cat # MAB14199).

    Immunofluorescence

    Flow Cytometry

  • Gene Info — CD99

    Entrez GeneID

    4267

    Protein Accession#

    P14209

    Gene Name

    CD99

    Gene Alias

    MIC2, MIC2X, MIC2Y

    Gene Description

    CD99 molecule

    Omim ID

    313470 450000

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    CD99 antigen|E2 antigen|MIC2 (monoclonal antibody 12E7)|OTTHUMP00000022840|T-cell surface glycoprotein E2|antigen identified by monoclonal 12E7, Y homolog|antigen identified by monoclonal antibodies 12E7, F21 and O13|surface antigen MIC2

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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