Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of mitochondrial and metabolic enzymes in tissue sections of normal, aged human cerebellar tissue with ACADVL monoclonal antibody, clone 6A9AF2 (Cat # MAB14192).
Immunocytochemical staining of HDFn cells with ACADVL monoclonal antibody, clone 6A9AF2 (Cat # MAB14192). Blue: nuclei. Red: secondary antibody. Target protein locates mainly in mitochondria.
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq