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TOP1 monoclonal antibody, clone 23B11

  • Catalog # : MAB14184
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of human TOP1.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to amino acids 699-725 of human TOP1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Size-exclusion chromatography purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (PEG, sucrose, 0.09% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Lane 1: Jurkat, Lane 2: MCF-7, Lane 3: HEK-293, Lane 4: NIH/3T3, Lane 5: NTERA-2 and Lane 6: HeLa cell lysates with TOP1 monoclonal antibody, clone 23B11 (Cat # MAB14184).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7150
  • Gene Name:
  • TOP1
  • Gene Alias:
  • TOPI
  • Gene Description:
  • topoisomerase (DNA) I
  • Gene Summary:
  • This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq
  • Other Designations:
  • DNA topoisomerase I,OTTHUMP00000031713,type I DNA topoisomerase
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