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TOP1 monoclonal antibody, clone 24.5

  • Catalog # : MAB14183
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human TOP1.
  • Immunogen:
  • Recombinant protein corresponding to N-terminus of human TOP1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A affinity purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunofluorescence
    Immunoprecipitation
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunofluorescence
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation analysis of Lane 1: HeLa (after immunoprecipitation), Lane 2: HeLa (negative immunoprecipitation control), Lane 3: HeLa (no immunoprecipitation), Lane 4: BT474 and Lane 5: T47D cell lysates with TOP1 monoclonal antibody, clone 24.5 (Cat # MAB14183).
  • Application Image
  • Western Blot
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 7150
  • Gene Name:
  • TOP1
  • Gene Alias:
  • TOPI
  • Gene Description:
  • topoisomerase (DNA) I
  • Gene Summary:
  • This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq
  • Other Designations:
  • DNA topoisomerase I,OTTHUMP00000031713,type I DNA topoisomerase
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