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HADHB monoclonal antibody, clone 5C3AB7

  • Catalog # : MAB14174
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human HADHB.
  • Immunogen:
  • Human HADHB.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Purified
  • Isotype:
  • IgG2
  • Recommend Usage:
    Immunocytochemistry (1 ug/mL)
    Western Blot (0.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES (0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of HepG2 with HADHB monoclonal antibody, clone 5C3AB7 (Cat # MAB14174).
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of HDFn cells with HADHB monoclonal antibody, clone 5C3AB7 (Cat # MAB14174). Blue: nuclei. Target protein locates mainly in mitochondria.
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3032
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
  • Gene Summary:
  • This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found; however, their full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit,3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit,acetyl-CoA acyltransferase,beta-ketothiolase,hydroxyacyl-Coenzyme A (CoA) dehydrogenase, beta subunit,mitochondrial
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