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Last updated: 2020/11/29
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TNNI3 monoclonal antibody, clone TPC-110 

  • Catalog # : MAB1417
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native human TNNI3.
  • Immunogen:
  • Native purified human TNNI3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Human Troponin I, amino acid sequence N24-40. Not reactive to human skeletal muscle Troponin I, human skeletal Troponin T, human cardiac Troponin T, or human Troponin C.
  • Form:
  • Liquid
  • Purification:
  • DEAE column chromatography
  • Activity:
  • Affinity Constant: 4 x 1010 l/mol.
  • Isotype:
  • IgG1
  • Recommend Usage:
  • For solid phase coating (capture) or enzyme conjugation (detection).
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 15 mM KPO4 buffer, 0.85% NaCl, pH 7.4 (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do Not Freeze. Precipitation may occur upon freezing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Sandwich ELISA
  • Application Image
  • Sandwich ELISA
  • Gene Information
  • Entrez GeneID:
  • 7137
  • Gene Name:
  • TNNI3
  • Gene Alias:
  • CMD2A,CMH7,MGC116817,RCM1,TNNC1,cTnI
  • Gene Description:
  • troponin I type 3 (cardiac)
  • Gene Summary:
  • Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
  • Other Designations:
  • familial hypertrophic cardiomyopathy 7,troponin I, cardiac
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