Mouse monoclonal antibody raised against full length recombinant human SOD1.
Recombinant protein corresponding to full length human SOD1.
Protein A affinity purification
Immunocytochemistry (2 ug/mL) Immunofluorescence (2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:20-1:200) Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
In PBS (30% glycerol, 1 mg/mL BSA, 0.05% sodium azide).
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) in the cytoplasm of human placenta (A) and in the nucleus and cytoplasm of human breast carcinoma (B) tissues (right) with SOD1 monoclonal antibody, clone 8B10 (Cat # MAB14165) compared to a negative control without primary antibody respectively (left).
Immunofluorescent staining in the cytoplasm and nucleus of HeLa (A), HepG2 (B) and 3T3-L1 (C) cells (right) with SOD1 monoclonal antibody, clone 8B10 (Cat # MAB14165) (Green) compared to a negative control without primary antibody respectively (left). Blue: nuclei. Red: F-actin.
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq
Cu /Zn superoxide dismutase,Cu/Zn superoxide dismutase,SOD, soluble,indophenoloxidase A,superoxide dismutase, cystolic