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HSD17B4 monoclonal antibody, clone 8E5AB11

  • Catalog # : MAB14139
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human HSD17B4.
  • Immunogen:
  • Human HSD17B4.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Purified
  • Isotype:
  • IgG3
  • Recommend Usage:
  • ELISA
    Immunocytochemistry (4 ug/mL)
    Immunoprecipitation
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES (0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of HDFn cells with HSD17B4 monoclonal antibody, clone 8E5AB11 (Cat # MAB14139). Red: secondary antibody. Target protein locates mainly in peroxisome.
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3295
  • Gene Name:
  • HSD17B4
  • Gene Alias:
  • DBP,MFE-2,SDR8C1
  • Gene Description:
  • hydroxysteroid (17-beta) dehydrogenase 4
  • Gene Summary:
  • The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq
  • Other Designations:
  • 17-beta-HSD IV,17-beta-hydroxysteroid dehydrogenase 4,17beta-estradiol dehydrogenase type IV,3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase,D-3-hydroxyacyl-CoA dehydratase,D-bifunctional protein, peroxisomal,beta-hydroxyacyl deh
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