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Last updated: 2016/10/16

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MAP2K4 monoclonal antibody, clone 2 E4

  • Catalog # : MAB14121
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human MAP2K4.
  • Immunogen:
  • Protein expressed in 293T cells transfected with human MAP2K4 expression vector.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunocytochemistry (1:50)
    Immunofluorescence (1:50)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 1 mg/mL BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Lane 1: 293T, Lane 2: HeLa, Lane 3: NIH3T3, Lane 4: COS7, Lane 5: K562, Lane 6: U2OS, Lane 7: NRK and Lane 8: NB4 cell lysates with MAP2K4 monoclonal antibody, clone 2 E4 (Cat # MAB14121).
  • Immunocytochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining shows specific expression in HeLa cells (A, shown in green) but not in negative control NRK cells (B) with MAP2K4 monoclonal antibody, clone 2 E4 (Cat # MAB14121). Blue: nuclei. Red: F-actin.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 6416
  • Gene Name:
  • MAP2K4
  • Gene Alias:
  • Gene Description:
  • mitogen-activated protein kinase kinase 4
  • Gene Summary:
  • This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq
  • Other Designations:
  • JNK activating kinase 1,JNK-activated kinase 1,MAP kinase kinase 4,MAPK/ERK kinase 4,SAPK/ERK kinase 1,c-Jun N-terminal kinase kinase 1,dual specificity mitogen-activated protein kinase kinase 4
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