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ECH1 monoclonal antibody, clone 9D11AF3

  • Catalog # : MAB14028
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human ECH1.
  • Immunogen:
  • ECH1 contains a peroxisomal targeting sequence at C-terminus and localizes to the peroxisome.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Purified
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA
    Immunocytochemistry (4 ug/mL)
    Immunoprecipitation
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES (0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of HDFn cells with ECH1 monoclonal antibody, clone 9D11AF3 (Cat # MAB14028). Blue: nuclei. Green: secondary antibody. Target protein locates mainly in mitochondria.
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1891
  • Gene Name:
  • ECH1
  • Gene Alias:
  • HPXEL
  • Gene Description:
  • enoyl Coenzyme A hydratase 1, peroxisomal
  • Gene Summary:
  • This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq
  • Other Designations:
  • delta3,5-delta2,4-dienoyl-CoA isomerase,dienoyl-CoA isomerase,peroxisomal enoyl-CoA hydratase 1,peroxisomal enoyl-coenzyme A hydratase-like protein
  • Gene Pathway
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