Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) in the membrane of human kidney (A) with CLDN10 monoclonal antibody, clone 4B8A12 (Cat # MAB14015) compared to a negative control without primary antibody (B).
Immunofluorescent staining of mouse lung tissue cryosection with CLDN10 monoclonal antibody, clone 4B8A12 (Cat # MAB14015) (Green). Blue: nuclei.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq