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TNFRSF1A monoclonal antibody, clone H398

  • Catalog # : MAB13968
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human TNFRSF1A.
  • Immunogen:
  • Recombinant protein corresponding to full length human TNFRSF1A.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes the 60 kDa TNF-receptor on human cells as well as its soluble fragment, and completely neutralizes the whole range of TNF effects.
  • Form:
  • Liquid
  • Purification:
  • Affinity chromatography
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunohistochemistry (Frozen sections) (1:150)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS.
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 7132
  • Gene Name:
  • TNFRSF1A
  • Gene Alias:
  • CD120a,FPF,MGC19588,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR1,TNFR55,TNFR60,p55,p55-R,p60
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 1A
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. [provided by RefSeq
  • Other Designations:
  • tumor necrosis factor binding protein 1,tumor necrosis factor receptor 1,tumor necrosis factor receptor type 1,tumor necrosis factor-alpha receptor
  • Related Disease
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