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GP1BA monoclonal antibody, clone HIP1 (FITC)

  • Catalog # : MAB13911
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human GP1BA.
  • Immunogen:
  • Human PBMCs of a patient suffering with CLL.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 17-22
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • FITC
  • Purification:
  • Protein A/G purification
  • Purity:
  • >90%
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (20 uL/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
  • Storage Instruction:
  • Store in the dark at 4°C. Avoid prolonged exposure to light.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of human platelets with GP1BA monoclonal antibody, clone HIP1 (FITC) (Cat # MAB13911).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2811
  • Gene Name:
  • GP1BA
  • Gene Alias:
  • BSS,CD42B,CD42b-alpha,GP1B,MGC34595
  • Gene Description:
  • glycoprotein Ib (platelet), alpha polypeptide
  • Gene Summary:
  • Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq
  • Other Designations:
  • platelet glycoprotein Ib alpha polypeptide,platelet membrane glycoprotein 1b-alpha subunit
  • Interactome
  • Interactome
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