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ITGAM monoclonal antibody, clone DCIS1/18 (OC-515)

  • Catalog # : MAB13801
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human ITGAM.
  • Immunogen:
  • Dendritic cells derived from human monocytes.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 165, 95
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • OC-515
  • Purification:
  • Protein A/G purification
  • Purity:
  • >90%
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry (5 uL/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
  • Storage Instruction:
  • Store in the dark at 4°C. Avoid prolonged exposure to light.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of human peripheral blood lymphocytes with ITGAM monoclonal antibody, clone DCIS1/18 (OC-515) (Cat # MAB13801).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3684
  • Gene Name:
  • ITGAM
  • Gene Alias:
  • CD11B,CR3A,MAC-1,MAC1A,MGC117044,MO1A,SLEB6
  • Gene Description:
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • Gene Summary:
  • This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • antigen CD11b (p170),complement component receptor 3, alpha,integrin alpha M,macrophage antigen alpha polypeptide,neutrophil adherence receptor alpha-M subunit
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