ITGAM monoclonal antibody, clone DCIS1/18 (PE)
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More Files
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Flow Cytometry
Flow cytometric analysis of human normal whole blood with ITGAM monoclonal antibody, clone DCIS1/18 (PE) (Cat # MAB13797).
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Specification
Product Description
Mouse monoclonal antibody raised against human ITGAM.
Immunogen
Dendritic cells derived from human monocytes.
Host
Mouse
Theoretical MW (kDa)
165, 95
Reactivity
Human
Form
Liquid
Conjugation
PE
Purification
Protein A/G purification
Purity
>90%
Isotype
IgG2a
Recommend Usage
Flow Cytometry (20 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of human normal whole blood with ITGAM monoclonal antibody, clone DCIS1/18 (PE) (Cat # MAB13797). -
Gene Info — ITGAM
Entrez GeneID
3684Protein Accession#
P11215Gene Name
ITGAM
Gene Alias
CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6
Gene Description
integrin, alpha M (complement component 3 receptor 3 subunit)
Omim ID
120980Gene Ontology
HyperlinkGene Summary
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
antigen CD11b (p170)|complement component receptor 3, alpha|integrin alpha M|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit
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Interactome
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Pathway
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