ITGAL monoclonal antibody, clone TP1/40 (FITC)
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More Files
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Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with ITGAL monoclonal antibody, clone TP1/40 (FITC) (Cat # MAB13784).
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Specification
Product Description
Mouse monoclonal antibody raised against human ITGAL.
Immunogen
PMA and Ionomycin activated human T cells blast.
Host
Mouse
Theoretical MW (kDa)
180
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
Protein A/G purification
Purity
>90%
Isotype
IgG1
Recommend Usage
Flow Cytometry (20 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (protein stabilizer, 0.09% sodium azide).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with ITGAL monoclonal antibody, clone TP1/40 (FITC) (Cat # MAB13784). -
Gene Info — ITGAL
Entrez GeneID
3683Protein Accession#
P20701Gene Name
ITGAL
Gene Alias
CD11A, LFA-1, LFA1A
Gene Description
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Omim ID
153370Gene Ontology
HyperlinkGene Summary
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
LFA-1 alpha|antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide|integrin alpha L|integrin gene promoter|lymphocyte function-associated antigen 1
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Interactome
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Pathway
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Disease
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