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HSP90B1 monoclonal antibody, clone HSP90B1/1192

  • Catalog # : MAB13447
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against full length recombinant human HSP90B1.
  • Immunogen:
  • Recombinant protein corresponding to full length human HSP90B1.
  • Host:
  • Rat
  • Theoretical MW (kDa):
  • 94
  • Reactivity:
  • Human
  • Specificity:
  • This monoclonal antibody is highly specific to HSP90B1 and shows minimal cross-reaction with other members of the HSP90 family.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
    Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast cancer with HSP90B1 monoclonal antibody, clone HSP90B1/1192 (Cat # MAB13447).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7184
  • Gene Name:
  • HSP90B1
  • Gene Alias:
  • ECGP,GP96,GRP94,TRA1
  • Gene Description:
  • heat shock protein 90kDa beta (Grp94), member 1
  • Gene Summary:
  • HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM
  • Other Designations:
  • Tumor rejection antigen-1 (gp96),endothelial cell (HBMEC) glycoprotein,glucose regulated protein, 94 kDa,heat shock protein 90kDa beta, member 1,tumor rejection antigen (gp96) 1
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