CDw75 monoclonal antibody, clone LN-1
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with CDw75 monoclonal antibody, clone LN-1 (Cat # MAB13432).
Flow Cytometry
Flow cytometric analysis of human lymphocytes with CDw75 monoclonal antibody, clone LN-1 (Cat # MAB13432) (Red) and isotype control (Green).
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Specification
Product Description
Mouse monoclonal antibody raised against native human CDw75.
Immunogen
Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes.
Host
Mouse
Theoretical MW (kDa)
46
Reactivity
Human
Form
Liquid
Purification
PEG precipitation
Isotype
IgM, kappa
Recommend Usage
Flow Cytometry (1-2 ug/million cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL for 30 min at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with CDw75 monoclonal antibody, clone LN-1 (Cat # MAB13432).Immunofluorescence
Flow Cytometry
Flow cytometric analysis of human lymphocytes with CDw75 monoclonal antibody, clone LN-1 (Cat # MAB13432) (Red) and isotype control (Green). -
Gene Info — ST6GAL1
Entrez GeneID
6480Protein Accession#
P15907Gene Name
ST6GAL1
Gene Alias
CD75, MGC48859, SIAT1, ST6GalI, ST6N
Gene Description
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
Omim ID
109675Gene Ontology
HyperlinkGene Summary
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq
Other Designations
CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase|ST6Gal I|alpha 2,6-ST|sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase)|sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase)
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Interactome
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Pathway
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Disease
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