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PODXL monoclonal antibody, clone 2A4

  • Catalog # : MAB13400
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human PODXL.
  • Immunogen:
  • Recombinant protein corresponding to intracellular, transmembrane, and part of the extracellular domain of human PODXL.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 165-170
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • PEG precipitation
  • Isotype:
  • IgM
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
    Immunofluorescence (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human angiosarcoma (A) and human placenta (B) with PODXL monoclonal antibody, clone 2A4 (Cat # MAB13400).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 5420
  • Gene Name:
  • PODXL
  • Gene Alias:
  • Gp200,MGC138240,PC,PCLP
  • Gene Description:
  • podocalyxin-like
  • Gene Summary:
  • This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq
  • Other Designations:
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