Histone H1 monoclonal antibody, clone AE-4
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil (A) and human ovarian carcinoma (B) with Histone H1 monoclonal antibody, clone AE-4 (Cat # MAB13301).
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Specification
Product Description
Mouse monoclonal antibody raised against native human Histone H1.
Immunogen
Nuclei of human leukemia biopsy cells.
Host
Mouse
Theoretical MW (kDa)
~30
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2a, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil (A) and human ovarian carcinoma (B) with Histone H1 monoclonal antibody, clone AE-4 (Cat # MAB13301).Immunofluorescence
Flow Cytometry
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Gene Info — H1F0
Entrez GeneID
3005Protein Accession#
P07305Gene Name
H1F0
Gene Alias
H10, H1FV, MGC5241
Gene Description
H1 histone family, member 0
Omim ID
142708Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. [provided by RefSeq
Other Designations
H1.0, H1(0), H1-0|OTTHUMP00000028818
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Interactome
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Disease
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