GFAP monoclonal antibody, clone ASTRO/789
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human GFAP.
Immunogen
Recombinant protein corresponding to full length human GFAP.
Host
Mouse
Theoretical MW (kDa)
~50
Reactivity
Human, Rat
Specificity
This monoclonal antibody shows no cross-reaction with other intermediate filament proteins.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human schwanoma (A), human cerebellum (B) and rat cerebellum (C) with GFAP monoclonal antibody, clone ASTRO/789 (Cat # MAB13278).Immunofluorescence
Flow Cytometry
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Gene Info — GFAP
Entrez GeneID
2670Protein Accession#
P14136Gene Name
GFAP
Gene Alias
FLJ45472
Gene Description
glial fibrillary acidic protein
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
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Interactome
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Disease
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