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CDKN1C monoclonal antibody, clone 57P06

  • Catalog # : MAB13251
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human CDKN1C.
  • Immunogen:
  • Recombinant protein corresponding to full length human CDKN1C.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 57
  • Reactivity:
  • Human
  • Specificity:
  • This monoclonal antibody shows no cross-reaction with CDKN1B.
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
    Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bladder carcinoma with CDKN1C monoclonal antibody, clone 57P06 (Cat # MAB13251).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 1028
  • Gene Name:
  • CDKN1C
  • Gene Alias:
  • BWCR,BWS,KIP2,WBS,p57
  • Gene Description:
  • cyclin-dependent kinase inhibitor 1C (p57, Kip2)
  • Gene Summary:
  • The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000011736,cyclin-dependent kinase inhibitor 1C
  • Gene Pathway
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