MVP monoclonal antibody, clone SPM280
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testicle tumor with MVP monoclonal antibody, clone SPM280 (Cat # MAB13192).
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Specification
Product Description
Mouse monoclonal antibody raised against native human MVP.
Immunogen
Native purified MVP from human breast cancer MCF-7 cells.
Host
Mouse
Theoretical MW (kDa)
104-110
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testicle tumor with MVP monoclonal antibody, clone SPM280 (Cat # MAB13192).Immunofluorescence
Flow Cytometry
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Gene Info — MVP
Entrez GeneID
9961Protein Accession#
Q14764Gene Name
MVP
Gene Alias
LRP, VAULT1
Gene Description
major vault protein
Omim ID
605088Gene Ontology
HyperlinkGene Summary
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq
Other Designations
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