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PAX6 monoclonal antibody, clone SPM612

  • Catalog # : MAB13134
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human PAX6.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-300 at N-terminus region of human PAX6.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 47
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
    Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach carcinoma with PAX6 monoclonal antibody, clone SPM612 (Cat # MAB13134).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 5080
  • Gene Name:
  • PAX6
  • Gene Alias:
  • AN,AN2,D11S812E,MGC17209,MGDA,WAGR
  • Gene Description:
  • paired box 6
  • Gene Summary:
  • This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000038833,OTTHUMP00000038834,OTTHUMP00000038835,OTTHUMP00000038836,OTTHUMP00000038837,OTTHUMP00000038838,OTTHUMP00000038839,OTTHUMP00000038840,paired box gene 6,paired box homeotic gene-6
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