Mouse monoclonal antibody raised against recombinant IL10.
Immunogen:
Recombinant protein corresponding to human IL10.
Host:
Mouse
Reactivity:
Human
Form:
Lyophilized
Isotype:
IgG1
Recommend Usage:
ELISA (1:20000) The optimal working dilution should be determined by the end user.
Storage Buffer:
Lyophilized from PBS.
Storage Instruction:
Store at 4°C on dry atmosphere. After reconstitution with 0.5 mL of deionized water, mix gently, wash the sides of the vial and wait 30-60 seconds before use. If not intended for use within a month, aliquot and store at -20°C. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq