CDH16 monoclonal antibody, clone SPM594
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human CDH16.
Immunogen
Recombinant protein corresponding to full length human CDH16.
Host
Mouse
Theoretical MW (kDa)
130
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human renal cell carcinoma using CDH16 monoclonal antibody, clone SPM594 (Cat # MAB13055).Immunofluorescence
Flow Cytometry
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Gene Info — CDH16
Entrez GeneID
1014Protein Accession#
O75309Gene Name
CDH16
Gene Alias
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Gene Description
cadherin 16, KSP-cadherin
Omim ID
603118Gene Ontology
HyperlinkGene Summary
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. [provided by RefSeq
Other Designations
KSP-cadherin|cadherin 16|kidney-specific cadherin
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