CDKN1C monoclonal antibody, clone SPM308
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate carcinoma using CDKN1C monoclonal antibody, clone SPM308 (Cat # MAB13041).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human CDKN1C.
Immunogen
Recombinant protein corresponding to full length human CDKN1C.
Host
Mouse
Theoretical MW (kDa)
57
Reactivity
Human
Specificity
This antibody shows no cross-reaction with p27Kip1.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate carcinoma using CDKN1C monoclonal antibody, clone SPM308 (Cat # MAB13041).Immunofluorescence
Flow Cytometry
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Gene Info — CDKN1C
Entrez GeneID
1028Protein Accession#
P49918Gene Name
CDKN1C
Gene Alias
BWCR, BWS, KIP2, WBS, p57
Gene Description
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011736|cyclin-dependent kinase inhibitor 1C
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Interactome
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Pathway
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Disease
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