Western Blot analysis of HEK293T cells transfected with the Lane 1: pCMV6-ENTRY control and Lane 2: pCMV6-ENTRY AQP1 cDNA for 48 hrs (5 ug/lane) using AQP1 monoclonal antibody, clone 1F3 (Cat # MAB13009).
Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. [provided by RefSeq
Colton blood group,aquaporin 1,aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group),channel-like integral membrane protein, 28-kDa