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Last updated: 2016/11/27

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TNFRSF11B monoclonal antibody, clone 98A1071

  • Catalog # : MAB12971
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human TNFRSF11B.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 20-37 of human TNFRSF11B.
  • Sequence:
  • TQETFPPKYLHYDEETSH
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Daudi cell lysate with TNFRSF11B monoclonal antibody, clone 98A1071 (Cat # MAB12971) at 1 ug/mL working concentration.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver (A) and human heart (B) with TNFRSF11B monoclonal antibody, clone 98A1071 (Cat # MAB12971) at 5 ug/mL working concentration.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4982
  • Gene Name:
  • TNFRSF11B
  • Gene Alias:
  • MGC29565,OCIF,OPG,TR1
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 11b
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • osteoclastogenesis inhibitory factor,osteoprotegerin
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