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BIRC7 monoclonal antibody, clone 88C570

  • Catalog # : MAB12961
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant human BIRC7.
  • Immunogen:
  • Recombinant protein corresponding to human BIRC7.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: BIRC7 transfected cell lysate and Lane 2: U266 cell lysate with BIRC7 monoclonal antibody, clone 88C570 (Cat # MAB12961) at 2 ug/mL working concentration.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human heart with BIRC7 monoclonal antibody, clone 88C570 (Cat # MAB12961) at 10 ug/mL working concentration.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • BIRC7
  • Gene Alias:
  • KIAP,LIVIN,ML-IAP,MLIAP,RNF50
  • Gene Description:
  • baculoviral IAP repeat-containing 7
  • Gene Summary:
  • The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031536,OTTHUMP00000031537,baculoviral IAP repeat-containing protein 7,kidney inhibitor of apoptosis protein,livin inhibitor of apoptosis,livin inhibitor-of-apoptosis,melanoma inhibitor of apoptosis protein
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