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GYPA/GYPB monoclonal antibody, clone HIR2

  • Catalog # : MAB12957
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human GYPA/GYPB.
  • Immunogen:
  • Human peripheral blood mononuclear cell (PBMC).
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Flow Cytometry
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney, red blood cells with GYPA/GYPB monoclonal antibody, clone HIR2 (Cat # MAB12957) at 1:50 dilution.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of human red blood cells with GYPA/GYPB monoclonal antibody, clone HIR2 (Cat # MAB12957).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2993
  • Gene Name:
  • GYPA
  • Gene Alias:
  • CD235a,GPA,GPErik,GPSAT,GpMiIII,HGpMiIII,HGpMiV,HGpMiX,HGpMiXI,HGpSta(C),MN,MNS
  • Gene Description:
  • glycophorin A (MNS blood group)
  • Gene Summary:
  • Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq
  • Other Designations:
  • Mi.V glycoprotein (24 AA),erythroid-lineage-specific membrane sialoglycoprotein,glycophorin A,glycophorin A (MN blood group),glycophorin A MNS blood group,glycophorin A, GPA,glycophorin Erik,glycophorin MiI,glycophorin MiIII,glycophorin MiV,glycophorin Mi
  • Gene Information
  • Entrez GeneID:
  • 2994
  • Gene Name:
  • GYPB
  • Gene Alias:
  • CD235b,GPB,GPB.NY,GYPHe.NY,HGpMiVI,MNS,SS
  • Gene Description:
  • glycophorin B (MNS blood group)
  • Gene Summary:
  • Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq
  • Other Designations:
  • Ss blood group,glycophorin B,glycophorin HeP2,glycophorin MiVI
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