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Last updated: 2017/8/13

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PMS2 monoclonal antibody, clone 163C1251

  • Catalog # : MAB12955
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of human PMS2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 623-639 of human PMS2.
  • Sequence:
  • SSLAKRIKQLHHEAQQS
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of NIH/3T3 cell lysate with PMS2 monoclonal antibody, clone 163C1251 (Cat # MAB12955) at 2 ug/mL working concentration.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast with PMS2 monoclonal antibody, clone 163C1251 (Cat # MAB12955) at 5 ug/mL working concentration.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5395
  • Gene Name:
  • PMS2
  • Gene Alias:
  • HNPCC4,PMS2CL,PMSL2
  • Gene Description:
  • PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
  • Gene Summary:
  • This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq
  • Other Designations:
  • DNA mismatch repair protein,H_DJ0042M02.9,PMS2 postmeiotic segregation increased 2,mismatch repair endonuclease,postmeiotic segregation increased 2
  • Gene Pathway
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