SUPT16H monoclonal antibody, clone 8D2
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human SUPT16H.
Immunogen
Recombinant protein corresponding to full length human SUPT16H.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG2a
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide).
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Hela cells with SUPT16H monoclonal antibody, clone 8D2 (Cat # MAB12948) followed by HRP-conjugated donkey anti-mouse secondary antibody and visualized by chemiluminescence detection system.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with SUPT16H monoclonal antibody, clone 8D2 (Cat # MAB12948) at 10 ug/mL working concentration. -
Gene Info — SUPT16H
Entrez GeneID
11198Protein Accession#
Q9Y5B9Gene Name
SUPT16H
Gene Alias
CDC68, FACT, FACTP140, FLJ10857, FLJ14010, FLJ34357, SPT16/CDC68
Gene Description
suppressor of Ty 16 homolog (S. cerevisiae)
Omim ID
605012Gene Ontology
HyperlinkGene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq
Other Designations
chromatin-specific transcription elongation factor large subunit|facilitates chromatin remodeling 140 kDa subunit
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Interactome
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