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SIPA1 monoclonal antibody, clone 331-9

  • Catalog # : MAB12893
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant human SIPA1.
  • Immunogen:
  • Recombinant protein corresponding to human SIPA1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Immunoprecipitation
    Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (50% glycerol).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Lane 1: Raji cells, Lane 2: HL-60 cells, Lane 3: Jurkat cells, Lane 4: HeLa cells and Lane 5: 293T cells with SIPA1 monoclonal antibody, clone 331-9 (Cat # MAB12893).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil (A) and human colon (B) with SIPA1 monoclonal antibody, clone 331-9 (Cat # MAB12893).
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 6494
  • Gene Name:
  • SIPA1
  • Gene Alias:
  • MGC102688,MGC17037,SPA1
  • Gene Description:
  • signal-induced proliferation-associated 1
  • Gene Summary:
  • The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq
  • Other Designations:
  • GTPase-activating protein Spa-1,p130 SPA-1,signal-induced proliferation-associated gene 1,signal-induced proliferation-associated protein 1
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