AVPR1A monoclonal antibody, clone 721CT25.2.1
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human AVPR1A.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 353-383 of human AVPR1A.
Host
Mouse
Reactivity
Human, Mouse
Form
Liquid
Purification
Euglobulin precipitation
Isotype
IgM
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: A549, Lane 2: MCF-7, Lane 3: HL-60 and Lane 4: mouse C2C12 (35 ug/lane) with AVPR1A monoclonal antibody, clone 721CT25.2.1 (Cat # MAB12875).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney (A) and human breast (B) with AVPR1A monoclonal antibody, clone 721CT25.2.1 (Cat # MAB12875). -
Gene Info — AVPR1A
Entrez GeneID
552Protein Accession#
P37288Gene Name
AVPR1A
Gene Alias
AVPR1
Gene Description
arginine vasopressin receptor 1A
Omim ID
600821Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq
Other Designations
SCCL vasopressin subtype 1a receptor|V1-vascular vasopressin receptor AVPR1A|V1a vasopressin receptor|antidiuretic hormone receptor 1A|vascular/hepatic-type arginine vasopressin receptor
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