Mouse monoclonal antibody raised against full length recombinant human FH.
Recombinant protein corresponding to full length human FH.
Protein A/G purification
Flow Cytometry (1:100) Immunofluorescence (1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Western Blot analysis of Lane 1: HepG2, Lane 2: HeLa, Lane 3: HT29, Lane 4: A549, Lane 5: COS7, Lane 6: Jurkat, Lane 7: MDCK, Lane 8: PC12 and Lane 9: MCF7 (35 ug/lane) with FH monoclonal antibody, clone 9G4 (Cat # MAB12873).
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq