FCGR2A monoclonal antibody, clone 13D7
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human FCGR2A.
Immunogen
Recombinant protein corresponding to full length human FCGR2A.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b
Recommend Usage
Immunofluorescence (1:100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Immunoprecipitation
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.3 (50% glycerol, 1% BSA, 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HEK293T cells transfected with the Lane 1: pCMV6-ENTRY control and Lane 2: pCMV6-ENTRY FCGR2A cDNA for 48 hrs (5 ug/lane) using FCGR2A monoclonal antibody, clone 13D7 (Cat # MAB12859).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta (A) and human spleen (B) with FCGR2A monoclonal antibody, clone 13D7 (Cat # MAB12859).Immunofluorescence
Immunofluorescent staining of COS-7 cells with FCGR2A monoclonal antibody, clone 13D7 (Cat # MAB12859) transiently transfected by pCMV6-ENTRY FCGR2A.Immunoprecipitation
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Gene Info — FCGR2A
Entrez GeneID
2212Protein Accession#
P12318Gene Name
FCGR2A
Gene Alias
CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2, MGC23887, MGC30032
Gene Description
Fc fragment of IgG, low affinity IIa, receptor (CD32)
Omim ID
146790Gene Ontology
HyperlinkGene Summary
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
Fc fragment of IgG, low affinity IIa, receptor|Fc fragment of IgG, low affinity IIa, receptor for (CD32)|Immunoglobulin G Fc receptor II|OTTHUMP00000032377
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Interactome
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