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ANK2 monoclonal antibody, clone S105-17

  • Catalog # : MAB12854
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of human ANK2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 203-496 of human ANK2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 200
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunocytochemistry
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot analysis of rat brain membrane lysate Lane 1: at 1:1000 dilution and Lane 2: no primary antibody (Negative control) (33 ug/lane) with ANK2 monoclonal antibody, clone S105-17 (Cat # MAB12854).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate (A) and human cerebellum (B) with ANK2 monoclonal antibody, clone S105-17 (Cat # MAB12854).
  • Immunocytochemistry
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 287
  • Gene Name:
  • ANK2
  • Gene Alias:
  • DKFZp686M09125,DKFZp686P0948,FLJ38277,LQT4
  • Gene Description:
  • ankyrin 2, neuronal
  • Gene Summary:
  • This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000163834,ankyrin 2,ankyrin B,ankyrin, brain,ankyrin, nonerythroid,ankyrin-2, nonerythrocytic,brank-2
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