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WHSC2 monoclonal antibody, clone 6B11H8

  • Catalog # : MAB12849
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human WHSC2.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 280-511 of human WHSC2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Immunocytochemistry (1:200-1:1000)
    Immunofluorescence
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.5% protein stabilizer, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western Blot analysis of WHSC2 recombinant protein with WHSC2 monoclonal antibody, clone 6B11H8 (Cat # MAB12849).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with WHSC2 monoclonal antibody, clone 6B11H8 (Cat # MAB12849) at 10 ug/mL working concentration.
  • Immunocytochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of HeLa cells with WHSC2 monoclonal antibody, clone 6B11H8 (Cat # MAB12849) (Green). Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • Flow Cytometry
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunocytochemistry
  • ELISA
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7469
  • Gene Name:
  • WHSC2
  • Gene Alias:
  • FLJ10442,FLJ25112,NELF-A,NELFA,P/OKcl.15
  • Gene Description:
  • Wolf-Hirschhorn syndrome candidate 2
  • Gene Summary:
  • This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq
  • Other Designations:
  • Wolf-Hirschhorn syndrome candidate 2 protein
  • Related Disease
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