GDF15 monoclonal antibody, clone 6D12.H10.E4
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Specification
Product Description
Rat monoclonal antibody raised against human GDF15.
Immunogen
Recombinant MBP-tagged protein corresponding to full length human GDF15.
Host
Rat
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.02 M K3PO4, 0.15 M NaCl, pH 7.2 (0.01% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with GDF15 monoclonal antibody, clone 6D12.H10.E4 (Cat # MAB12728) at 10 ug/mL working concentration.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GDF15
Entrez GeneID
9518Gene Name
GDF15
Gene Alias
GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Gene Description
growth differentiation factor 15
Omim ID
605312Gene Ontology
HyperlinkGene Summary
Bone morphogenetic proteins (e.g., BMP5; MIM 112265) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM
Other Designations
NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1|PTGF-beta|prostate differentiation factor
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Interactome
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Disease
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