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TLR9 monoclonal antibody, clone 72-1665

  • Catalog # : MAB12707
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against human TLR9.
  • Immunogen:
  • Huamn TLR9
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Flow Cytometry
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL)
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In aqueous buffer (Stabilizer, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with TLR9 monoclonal antibody, clone 72-1665 (Cat # MAB12707) at 20 ug/mL working concentration.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HEK 293 parent cells (top histogram) and hTLR9 transfected cells (bottom histogram) with either anti-rat IgG-FITC alone (thin line) or TLR9 monoclonal antibody, clone 72-1665 (Cat # MAB12707) (thick line) followed by FITC-conjugated anti-rat IgG as the secondary antibody.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Gene Name:
  • TLR9
  • Gene Alias:
  • CD289
  • Gene Description:
  • toll-like receptor 9
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq
  • Other Designations:
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