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PRDX3 monoclonal antibody, clone 12B

  • Catalog # : MAB12701
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human PRDX3.
  • Immunogen:
  • Recombinant protein corresponding to full length human PRDX3.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 0.15 M NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: HeLa cell lysate, Lane 2: 293T cell lysate, Lane 3: Mouse Brain tissue lysate and Lane 4: Mouse Liver tissue lysate with PRDX3 monoclonal antibody, clone 12B (Cat # MAB12701).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with PRDX3 monoclonal antibody, clone 12B (Cat # MAB12701) at 1:200 dilution.
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunocytochemistry
  • Gene Information
  • Gene Name:
  • PRDX3
  • Gene Alias:
  • AOP-1,AOP1,MER5,MGC104387,MGC24293,PRO1748,SP-22
  • Gene Description:
  • peroxiredoxin 3
  • Gene Summary:
  • This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020590,antioxidant protein 1,thioredoxin-dependent peroxide reductase
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