Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human brain, cerebellum, Purkinje with SLC38A1 monoclonal antibody, clone S104-32 (Cat # MAB12695) at 10 ug/mL working concentration.
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM