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REN monoclonal antibody, clone 7D3-E3

  • Catalog # : MAB12692
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human REN.
  • Immunogen:
  • Recombinant protein corresponding to full length human REN.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • IgG purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.05 M Na3PO4, 0.1 M NaCl, pH 6.6 (1 mM EDTA).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney, tubules with REN monoclonal antibody, clone 7D3-E3 (Cat # MAB12692) at 10 ug/mL working concentration.
  • ELISA
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5972
  • Gene Name:
  • REN
  • Gene Alias:
  • FLJ10761
  • Gene Description:
  • renin
  • Gene Summary:
  • Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000034311,angiotensin-forming enzyme,angiotensinogenase,renin precursor, renal
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